Low expression of IL-18 and IL-18 receptor in human skeletal muscle is associated with systemic and intramuscular lipid metabolism—Role of HIV lipodystrophy

INTRODUCTION: Interleukin (IL)-18 is involved in regulation of lipid and glucose metabolism. Mice lacking whole-body IL-18 signalling are prone to develop weight gain and insulin resistance, a phenotype which is associated with impaired fat oxidation and ectopic skeletal muscle lipid deposition. IL-...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Lindegaard, Birgitte, Hvid, Thine, Wolsk Mygind, Helene, Hartvig-Mortensen, Ole, Grøndal, Thomas, Abildgaard, Julie, Gerstoft, Jan, Pedersen, Bente Klarlund, Baranowski, Marcin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771554/
https://ncbi.nlm.nih.gov/pubmed/29342149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186755
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