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Redefining the endophenotype concept to accommodate transdiagnostic vulnerabilities and etiological complexity

In psychopathology research, endophenotypes are a subset of biomarkers that indicate genetic vulnerability independent of clinical state. To date, an explicit expectation is that endophenotypes be specific to single disorders. We evaluate this expectation considering recent advances in psychiatric g...

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Detalhes bibliográficos
Publicado no:Biomark Med
Main Authors: Beauchaine, Theodore P, Constantino, John N
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771461/
https://ncbi.nlm.nih.gov/pubmed/28891303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/bmm-2017-0002
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