Colocalization of Galectin-3 With CD147 Is Associated With Increased Gelatinolytic Activity in Ulcerating Human Corneas

PURPOSE: Galectin-3 is a carbohydrate-binding protein known to promote expression of matrix metalloproteinases, a hallmark of ulceration, through interaction with the extracellular matrix metalloproteinase inducer CD147. The aim of this study was to investigate the distribution of galectin-3 in corn...

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Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Cruzat, Andrea, Gonzalez-Andrades, Miguel, Mauris, Jérôme, AbuSamra, Dina B., Chidambaram, Preethi, Kenyon, Kenneth R., Chodosh, James, Dohlman, Claes H., Argüeso, Pablo
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2018
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Cornea
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771460/
https://ncbi.nlm.nih.gov/pubmed/29340650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-23196
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