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Using mitoribosomal profiling to investigate human mitochondrial translation

Background: Gene expression in human mitochondria has various idiosyncratic features. One of these was recently revealed as the unprecedented recruitment of a mitochondrially-encoded tRNA as a structural component of the large mitoribosomal subunit. In porcine particles this is mt-tRNA (Phe) whilst...

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Bibliographic Details
Published in:Wellcome Open Res
Main Authors: Gao, Fei, Wesolowska, Maria, Agami, Reuven, Rooijers, Koos, Loayza-Puch, Fabricio, Lawless, Conor, Lightowlers, Robert N., Chrzanowska-Lightowlers, Zofia M. A.
Format: Artigo
Language:Inglês
Published: F1000 Research Limited 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771143/
https://ncbi.nlm.nih.gov/pubmed/29387808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.13119.2
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