Seed‐induced Aβ deposition is modulated by microglia under environmental enrichment in a mouse model of Alzheimer's disease

Alzheimer's disease (AD) is characterized by severe neuronal loss as well as the accumulation of amyloid‐β (Aβ), which ultimately leads to plaque formation. Although there is now a general agreement that the aggregation of Aβ can be initiated by prion‐like seeding, the impact and functional con...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:EMBO J
Päätekijät: Ziegler‐Waldkirch, Stephanie, d′Errico, Paolo, Sauer, Jonas‐Frederic, Erny, Daniel, Savanthrapadian, Shakuntala, Loreth, Desirée, Katzmarski, Natalie, Blank, Thomas, Bartos, Marlene, Prinz, Marco, Meyer‐Luehmann, Melanie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2017
Aiheet:
Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770788/
https://ncbi.nlm.nih.gov/pubmed/29229786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797021
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