Running‐wheel activity delays mitochondrial respiratory flux decline in aging mouse muscle via a post‐transcriptional mechanism

Loss of mitochondrial respiratory flux is a hallmark of skeletal muscle aging, contributing to a progressive decline of muscle strength. Endurance exercise alleviates the decrease in respiratory flux, both in humans and in rodents. Here, we dissect the underlying mechanism of mitochondrial flux decl...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Stolle, Sarah, Ciapaite, Jolita, Reijne, Aaffien C., Talarovicova, Alzbeta, Wolters, Justina C., Aguirre‐Gamboa, Raúl, van der Vlies, Pieter, de Lange, Kim, Neerincx, Pieter B., van der Vries, Gerben, Deelen, Patrick, Swertz, Morris A., Li, Yang, Bischoff, Rainer, Permentier, Hjalmar P., Horvatovitch, Peter L., Groen, Albert K., van Dijk, Gertjan, Reijngoud, Dirk‐Jan, Bakker, Barbara M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770778/
https://ncbi.nlm.nih.gov/pubmed/29120091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12700
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