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Vaccine Delivery: Turning the Old Adjuvant from Gel to Nanoparticles to Amplify CD8(+) T Cell Responses (Adv. Sci. 1/2018)

Alum, the well‐known vaccine adjuvant with a long history of clinical use, is changed from a “gel” to nanoparticles. This changes its mechanism of action from a “depot” that resides at the injection site, to nanoparticles that transport antigen and adjuvant into the lymph node. As reported by Xun Su...

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Bibliografiska uppgifter
I publikationen:Adv Sci (Weinh)
Huvudupphovsmän: Jiang, Hao, Wang, Qin, Li, Lin, Zeng, Qin, Li, Hanmei, Gong, Tao, Zhang, Zhirong, Sun, Xun
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770673/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201870001
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