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A pharmacological screen for compounds that rescue the developmental lethality of a Drosophila ATM mutant
Ataxia-telangiectasia (A-T) is a neurodegenerative disease caused by mutation of the A-T mutated (ATM) gene. ATM encodes a protein kinase that is activated by DNA damage and phosphorylates many proteins, including those involved in DNA repair, cell cycle control, and apoptosis. Characteristic biolog...
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| Publicado no: | PLoS One |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5770031/ https://ncbi.nlm.nih.gov/pubmed/29338042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190821 |
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