Bax-inhibiting peptide attenuates bleomycin-induced lung injury in mice

Bax is a pro-apoptotic member of the Bcl-2 family of proteins, and plays a central role in mitochondria-dependent apoptosis. Several lines of evidence have implied that Bax is involved in both epithelial apoptosis and fibroblast proliferation in idiopathic pulmonary fibrosis; however, the mechanisms...

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Dettagli Bibliografici
Pubblicato in:Biol Open
Autori principali: Suzuki, Kunihiro, Yanagihara, Toyoshi, Yokoyama, Tetsuya, Maeyama, Takashige, Ogata-Suetsugu, Saiko, Arimura-Omori, Masako, Mikumo, Hironori, Hamada, Naoki, Harada, Eiji, Kuwano, Kazuyoshi, Harada, Taishi, Nakanishi, Yoichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2017
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769644/
https://ncbi.nlm.nih.gov/pubmed/29138212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.026005
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