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The silencing of LncRNA-H19 decreases chemoresistance of human glioma cells to temozolomide by suppressing epithelial-mesenchymal transition via the Wnt/β-Catenin pathway
INTRODUCTION: Temozolomide (TMZ) is commonly used for glioma chemotherapy. However, TMZ resistance limits the therapeutic effect of TMZ in glioma treatment. LncRNA-H19 acts as an oncogenic LncRNA in some types of cancers and has been reported to be up-regulated in glioma. MATERIALS AND METHODS: In o...
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Publicado no: | Onco Targets Ther |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Dove Medical Press
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5769571/ https://ncbi.nlm.nih.gov/pubmed/29391808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S154339 |
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