Effects of hypoxia and hyperoxia on the differential expression of VEGF-A isoforms and receptors in Idiopathic Pulmonary Fibrosis (IPF)

Dysregulation of VEGF-A bioavailability has been implicated in the development of lung injury/fibrosis, exemplified by Idiopathic Pulmonary Fibrosis (IPF). VEGF-A is a target of the hypoxic response via its translational regulation by HIF-1α. The role of hypoxia and hyperoxia in the development and...

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Bibliographic Details
Published in:Respir Res
Main Authors: Barratt, Shaney L., Blythe, Thomas, Ourradi, Khadija, Jarrett, Caroline, Welsh, Gavin I., Bates, David O., Millar, Ann B.
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
Subjects:
Letter to the Editor
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769544/
https://ncbi.nlm.nih.gov/pubmed/29334947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0711-x
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