Genetic variants of prospectively demonstrated phenocopies in BRCA1/2 kindreds

BACKGROUND: In kindreds carrying path_BRCA1/2 variants, some women in these families will develop cancer despite testing negative for the family’s pathogenic variant. These families may have additional genetic variants, which not only may increase the susceptibility of the families’ path_BRCA1/2, bu...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Hered Cancer Clin Pract
Auteurs principaux: Dominguez-Valentin, Mev, Evans, D. Gareth R., Nakken, Sigve, Tubeuf, Hélène, Vodak, Daniel, Ekstrøm, Per Olaf, Nissen, Anke M., Morak, Monika, Holinski-Feder, Elke, Martins, Alexandra, Møller, Pål, Hovig, Eivind
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769521/
https://ncbi.nlm.nih.gov/pubmed/29371908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13053-018-0086-0
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires