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Epidermal Wnt signalling regulates transcriptome heterogeneity and proliferative fate in neighbouring cells

BACKGROUND: Canonical Wnt/beta-catenin signalling regulates self-renewal and lineage selection within the mammalian epidermis. Although the transcriptional response of keratinocytes that receive a Wnt signal is well characterized, little is known about the mechanism by which keratinocytes in proximi...

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Vydáno v:Genome Biol
Hlavní autoři: Ghahramani, Arsham, Donati, Giacomo, Luscombe, Nicholas M., Watt, Fiona M.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769491/
https://ncbi.nlm.nih.gov/pubmed/29334988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1384-y
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