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Ensemble genomic analysis in human lung tissue identifies novel genes for chronic obstructive pulmonary disease

BACKGROUND: Genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) significantly associated with chronic obstructive pulmonary disease (COPD). However, many genetic variants show suggestive evidence for association but do not meet the strict threshold for genom...

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Detalhes bibliográficos
Publicado no:Hum Genomics
Main Authors: Morrow, Jarrett D., Cho, Michael H., Platig, John, Zhou, Xiaobo, DeMeo, Dawn L., Qiu, Weiliang, Celli, Bartholome, Marchetti, Nathaniel, Criner, Gerard J., Bueno, Raphael, Washko, George R., Glass, Kimberly, Quackenbush, John, Silverman, Edwin K., Hersh, Craig P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769240/
https://ncbi.nlm.nih.gov/pubmed/29335020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-018-0132-z
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