Porcine reproductive and respiratory syndrome virus suppresses post-transcriptionally the protein expression of IFN-β by upregulating cellular microRNAs in porcine alveolar macrophages in vitro

Porcine reproductive and respiratory syndrome virus (PRRSV) has been recognized to inhibit the response of type I interferon (IFN) both in vivo and in vitro. However, the post-transcriptional mechanism by which PRRSV suppresses type I IFN induction in virus-infected host cells remains unclear. The p...

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Vydáno v:Exp Ther Med
Hlavní autoři: Wang, Lilin, Zhou, Lei, Hu, Dongmei, Ge, Xinna, Guo, Xin, Yang, Hanchun
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769220/
https://ncbi.nlm.nih.gov/pubmed/29387185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5397
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