β-arrestin 2 attenuates lipopolysaccharide-induced liver injury via inhibition of TLR4/NF-κB signaling pathway-mediated inflammation in mice

AIM: To study the role and the possible mechanism of β-arrestin 2 in lipopolysaccharide (LPS)-induced liver injury in vivo and in vitro. METHODS: Male β-arrestin 2(+/+) and β-arrestin 2(-/-) C57BL/6J mice were used for in vivo experiments, and the mouse macrophage cell line RAW264.7 was used for in...

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Dettagli Bibliografici
Pubblicato in:World J Gastroenterol
Autori principali: Jiang, Meng-Ping, Xu, Chun, Guo, Yun-Wei, Luo, Qian-Jiang, Li, Lin, Liu, Hui-Ling, Jiang, Jie, Chen, Hui-Xin, Wei, Xiu-Qing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Baishideng Publishing Group Inc 2018
Soggetti:
Basic Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768940/
https://ncbi.nlm.nih.gov/pubmed/29375207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v24.i2.216
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