JAK/STAT-1 Signaling Is Required for Reserve Intestinal Stem Cell Activation during Intestinal Regeneration Following Acute Inflammation

The intestinal epithelium serves as an essential barrier to the outside world and is maintained by functionally distinct populations of rapidly cycling intestinal stem cells (CBC ISCs) and slowly cycling, reserve ISCs (r-ISCs). Because disruptions in the epithelial barrier can result from pathologic...

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Publié dans:Stem Cell Reports
Auteurs principaux: Richmond, Camilla A., Rickner, Hannah, Shah, Manasvi S., Ediger, Tracy, Deary, Luke, Zhou, Fanny, Tovaglieri, Alessio, Carlone, Diana L., Breault, David T.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768934/
https://ncbi.nlm.nih.gov/pubmed/29276155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.11.015
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