Breast Cancers Activate Stromal Fibroblast-Induced Suppression of Progenitors in Adjacent Normal Tissue

Human breast cancer cells are known to activate adjacent “normal-like” cells to enhance their own growth, but the cellular and molecular mechanisms involved are poorly understood. We now show by both phenotypic and functional measurements that normal human mammary progenitor cells are significantly...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Chatterjee, Sumanta, Basak, Pratima, Buchel, Edward, Safneck, Janice, Murphy, Leigh C., Mowat, Michael, Kung, Sam K., Eirew, Peter, Eaves, Connie J., Raouf, Afshin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768884/
https://ncbi.nlm.nih.gov/pubmed/29233553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.11.002
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