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Transcriptomic signatures of cellular and humoral immune responses in older adults after seasonal influenza vaccination identified by data-driven clustering

PBMC transcriptomes after influenza vaccination contain valuable information about factors affecting vaccine responses. However, distilling meaningful knowledge out of these complex datasets is often difficult and requires advanced data mining algorithms. We investigated the use of the data-driven W...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Voigt, Emily A., Grill, Diane E., Zimmermann, Michael T., Simon, Whitney L., Ovsyannikova, Inna G., Kennedy, Richard B., Poland, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768803/
https://ncbi.nlm.nih.gov/pubmed/29335477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17735-x
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