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Gene and MicroRNA Perturbations of Cellular Response to Pemetrexed Implicate Biological Networks and Enable Imputation of Response in Lung Adenocarcinoma

Pemetrexed is indicated for non-small cell lung carcinoma and mesothelioma, but often has limited efficacy due to drug resistance. To probe the molecular mechanisms underlying chemotherapeutic response, we performed mRNA and microRNA (miRNA) expression profiling of pemetrexed treated and untreated l...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Gamazon, Eric R., Trendowski, Matthew R., Wen, Yujia, Wing, Claudia, Delaney, Shannon M., Huh, Won, Wong, Shan, Cox, Nancy J., Dolan, M. Eileen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768793/
https://ncbi.nlm.nih.gov/pubmed/29335598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-19004-3
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