High-resolution TADs reveal DNA sequences underlying genome organization in flies

Despite an abundance of new studies about topologically associating domains (TADs), the role of genetic information in TAD formation is still not fully understood. Here we use our software, HiCExplorer (hicexplorer.readthedocs.io) to annotate >2800 high-resolution (570 bp) TAD boundaries in Droso...

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Publicat a:Nat Commun
Autors principals: Ramírez, Fidel, Bhardwaj, Vivek, Arrigoni, Laura, Lam, Kin Chung, Grüning, Björn A., Villaveces, José, Habermann, Bianca, Akhtar, Asifa, Manke, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768762/
https://ncbi.nlm.nih.gov/pubmed/29335486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02525-w
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