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High-resolution TADs reveal DNA sequences underlying genome organization in flies

Despite an abundance of new studies about topologically associating domains (TADs), the role of genetic information in TAD formation is still not fully understood. Here we use our software, HiCExplorer (hicexplorer.readthedocs.io) to annotate >2800 high-resolution (570 bp) TAD boundaries in Droso...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ramírez, Fidel, Bhardwaj, Vivek, Arrigoni, Laura, Lam, Kin Chung, Grüning, Björn A., Villaveces, José, Habermann, Bianca, Akhtar, Asifa, Manke, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768762/
https://ncbi.nlm.nih.gov/pubmed/29335486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02525-w
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