Metabolic Linkage and Correlations to Storage Capacity in Erythrocytes from Glucose 6-Phosphate Dehydrogenase-Deficient Donors

OBJECTIVE: In glucose 6-phosphate dehydrogenase (G6PD) deficiency, decreased NADPH regeneration in the pentose phosphate pathway and subnormal levels of reduced glutathione result in insufficient antioxidant defense, increased susceptibility of red blood cells (RBCs) to oxidative stress, and acute h...

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Detalhes bibliográficos
Publicado no:Front Med (Lausanne)
Main Authors: Reisz, Julie A., Tzounakas, Vassilis L., Nemkov, Travis, Voulgaridou, Artemis I., Papassideri, Issidora S., Kriebardis, Anastasios G., D’Alessandro, Angelo, Antonelou, Marianna H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768619/
https://ncbi.nlm.nih.gov/pubmed/29376053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2017.00248
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