Pluripotent state transitions coordinate morphogenesis in mouse and human embryos

The foundations of mammalian development lie in a cluster of embryonic epiblast stem cells that, in response to extracellular matrix signalling, undergo epithelialization creating an apical surface in contact with a cavity1,2, a fundamental event for all subsequent development. Concomitantly, epibla...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Shahbazi, Marta N., Scialdone, Antonio, Skorupska, Natalia, Weberling, Antonia, Recher, Gaelle, Zhu, Meng, Jedrusik, Agnieszka, Devito, Liani G., Noli, Laila, Macaulay, Iain C., Buecker, Christa, Khalaf, Yakoub, Ilic, Dusko, Voet, Thierry, Marioni, John C., Zernicka-Goetz, Magdalena
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768241/
https://ncbi.nlm.nih.gov/pubmed/29186120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24675
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