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Pluripotent state transitions coordinate morphogenesis in mouse and human embryos
The foundations of mammalian development lie in a cluster of embryonic epiblast stem cells that, in response to extracellular matrix signalling, undergo epithelialization creating an apical surface in contact with a cavity1,2, a fundamental event for all subsequent development. Concomitantly, epibla...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5768241/ https://ncbi.nlm.nih.gov/pubmed/29186120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24675 |
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