Pluripotent state transitions coordinate morphogenesis in mouse and human embryos

The foundations of mammalian development lie in a cluster of embryonic epiblast stem cells that, in response to extracellular matrix signalling, undergo epithelialization creating an apical surface in contact with a cavity1,2, a fundamental event for all subsequent development. Concomitantly, epibla...

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Bibliografiska uppgifter
I publikationen:Nature
Huvudupphovsmän: Shahbazi, Marta N., Scialdone, Antonio, Skorupska, Natalia, Weberling, Antonia, Recher, Gaelle, Zhu, Meng, Jedrusik, Agnieszka, Devito, Liani G., Noli, Laila, Macaulay, Iain C., Buecker, Christa, Khalaf, Yakoub, Ilic, Dusko, Voet, Thierry, Marioni, John C., Zernicka-Goetz, Magdalena
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768241/
https://ncbi.nlm.nih.gov/pubmed/29186120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24675
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