Pluripotent state transitions coordinate morphogenesis in mouse and human embryos

The foundations of mammalian development lie in a cluster of embryonic epiblast stem cells that, in response to extracellular matrix signalling, undergo epithelialization creating an apical surface in contact with a cavity1,2, a fundamental event for all subsequent development. Concomitantly, epibla...

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Vydáno v:Nature
Hlavní autoři: Shahbazi, Marta N., Scialdone, Antonio, Skorupska, Natalia, Weberling, Antonia, Recher, Gaelle, Zhu, Meng, Jedrusik, Agnieszka, Devito, Liani G., Noli, Laila, Macaulay, Iain C., Buecker, Christa, Khalaf, Yakoub, Ilic, Dusko, Voet, Thierry, Marioni, John C., Zernicka-Goetz, Magdalena
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768241/
https://ncbi.nlm.nih.gov/pubmed/29186120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24675
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