Targeting polyelectrolyte networks in purulent body fluids to modulate bactericidal properties of some antibiotics

The response of the human immune system to most bacterial infections results in accumulation of neutrophils at infection sites that release a significant quantity of DNA and F-actin. Both are negatively charged polyelectrolytes that can interact with positively charged host defense molecules such as...

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Bibliografiske detaljer
Udgivet i:Infect Drug Resist
Main Authors: Bucki, Robert, Durnaś, Bonita, Wątek, Marzena, Piktel, Ewelina, Cruz, Katrina, Wolak, Przemysław, Savage, Paul B, Janmey, Paul A
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768182/
https://ncbi.nlm.nih.gov/pubmed/29391814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S145337
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