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Celastrus orbiculatus extracts induce apoptosis and inhibit invasion by targeting the maspin gene in human gastric adenocarcinoma cells

Celastrus orbiculatus Thunb. has been used as a remedy against cancer and inflammatory diseases for thousands of years in China. Maspin is expressed in normal cells and downregulated in prostate tumor cells. The underlying mechanisms between C. orbiculatus extract (COE) and maspin remain unclear. In...

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Bibliographische Detailangaben
Veröffentlicht in:Oncol Lett
Hauptverfasser: Qian, Yayun, Lu, Songhua, Shi, Youyang, Zhao, Xueyu, Yang, Ting, Jin, Feng, Liu, Yanqing
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768137/
https://ncbi.nlm.nih.gov/pubmed/29387218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7341
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