Characteristics of doxorubicin-selected multidrug-resistant human leukemia HL-60 cells with tolerance to arsenic trioxide and contribution of leukemia stem cells

The present study selected and characterized a multidrug-resistant HL-60 human acute promyelocytic leukemia cell line, HL-60/RS, by exposure to stepwise incremental doses of doxorubicin. The drug-resistant HL-60/RS cells exhibited 85.68-fold resistance to doxorubicin and were cross-resistant to othe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncol Lett
Prif Awduron: Chen, Jing, Wei, Hulai, Cheng, Jie, Xie, Bei, Wang, Bei, Yi, Juan, Tian, Baoying, Liu, Zhuan, Wang, Feifei, Zhang, Zhewen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2018
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768105/
https://ncbi.nlm.nih.gov/pubmed/29399180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7353
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