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Mitochondrial pathway-mediated apoptosis is associated with erlotinib-induced cytotoxicity in hepatic cells

For advanced non-small-cell lung cancer (NSCLC) with mutations to the epidermal growth factor receptor (EGFR), EGFR tyrosine kinase inhibitors, including erlotinib are indicated for the first-line treatment. Liver injury is one of the multiple adverse effects of erlotinib and may affect its safety....

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Chen, Xueqin, Yang, Shaoyu, Pan, Yuelong, Li, Xin, Ma, Shenglin
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768067/
https://ncbi.nlm.nih.gov/pubmed/29387241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7359
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