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A hereditary spastic paraplegia–associated atlastin variant exhibits defective allosteric coupling in the catalytic core
The dynamin-related GTPase atlastin (ATL) catalyzes membrane fusion of the endoplasmic reticulum and thus establishes a network of branched membrane tubules. When ATL function is compromised, the morphology of the endoplasmic reticulum deteriorates, and these defects can result in neurological disor...
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| Veröffentlicht in: | J Biol Chem |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5767872/ https://ncbi.nlm.nih.gov/pubmed/29180453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000380 |
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