Structure and function of the Leptospira interrogans peroxide stress regulator (PerR), an atypical PerR devoid of a structural metal-binding site

Peroxide sensing is essential for bacterial survival during aerobic metabolism and host infection. Peroxide stress regulators (PerRs) are homodimeric transcriptional repressors with each monomer typically containing both structural and regulatory metal-binding sites. PerR binding to gene promoters i...

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Udgivet i:J Biol Chem
Main Authors: Kebouchi, Mounira, Saul, Frederick, Taher, Raléb, Landier, Annie, Beaudeau, Bénédicte, Dubrac, Sarah, Weber, Patrick, Haouz, Ahmed, Picardeau, Mathieu, Benaroudj, Nadia
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767856/
https://ncbi.nlm.nih.gov/pubmed/29146596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.804443
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