Genomic Region Containing Toll-Like Receptor Genes Has a Major Impact on Total IgM Antibodies Including KLH-Binding IgM Natural Antibodies in Chickens

Natural antibodies (NAb) are antigen binding antibodies present in individuals without a previous exposure to this antigen. Keyhole limpet hemocyanin (KLH)-binding NAb levels were previously associated with survival in chickens. This suggests that selective breeding for KLH-binding NAb may increase...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Berghof, Tom V. L., Visker, Marleen H. P. W., Arts, Joop A. J., Parmentier, Henk K., van der Poel, Jan J., Vereijken, Addie L. J., Bovenhuis, Henk
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767321/
https://ncbi.nlm.nih.gov/pubmed/29375555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01879
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