Traditional Herbal Medicine-Derived Sulforaphene LFS-01 Reverses Colitis in Mice by Selectively Altering the Gut Microbiota and Promoting Intestinal Gamma-Delta T Cells

Sulforaphene (LFS-01) is a natural compound derived from traditional herbal medicine. Here, we show that oral administration of LFS-01 is able to dramatically alter the skewed gut microbiota and reverse colitis in model mice associated with an increase of intestinal γδT cells. Through 16S rDNA seque...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Li, Ming, Gao, Jiali, Tang, Yan, Liu, Meishuo, Wu, Sijin, Qu, Kunli, Long, Xiangyu, Li, Huajun, Liu, Min, Liu, Yinhui, Yuan, Jieli, Mao, Lei, Liu, Yu, Zheng, Xiliang, Wang, Erkang, Wang, Jin, Yang, Yongliang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767259/
https://ncbi.nlm.nih.gov/pubmed/29375374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00959
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