Characterization of early-onset motor deficits in the Pink1 −/− mouse model of Parkinson disease

In Parkinson disease (PD), a complex neurodegenerative disorder that affects nearly 10 million people worldwide, motor skills are significantly impaired. However, onset and progression of motor deficits and the neural correlates of these deficits are poorly understood. We used a genetic mouse model...

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Detalhes bibliográficos
Publicado no:Brain Res
Main Authors: Kelm-Nelson, Cynthia A., Brauer, Alexander F.L., Barth, Kelsey J., Lake, Jacob M., Sinnen, Mackenzie L. K., Stehula, Forrest J., Muslu, Cagla, Marongiu, Roberta, Kaplitt, Michael G., Ciucci, Michelle R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767140/
https://ncbi.nlm.nih.gov/pubmed/29229503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2017.12.002
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