The guanine nucleotide exchange factor Arf-like protein 13b is essential for assembly of the mouse photoreceptor transition zone and outer segment

Arf-like protein 13b (ARL13b) is a small GTPase that functions as a guanosine nucleotide exchange factor (GEF) for ARL3-GDP. ARL13b is located exclusively in photoreceptor outer segments (OS) presumably anchored to discs by palmitoylation, whereas ARL3 is an inner segment cytoplasmic protein. Hypomo...

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Hanke-Gogokhia, Christin, Wu, Zhijian, Sharif, Ali, Yazigi, Hussein, Frederick, Jeanne M., Baehr, Wolfgang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2017
Aiheet:
Molecular Bases of Disease
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766971/
https://ncbi.nlm.nih.gov/pubmed/29089384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000141
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