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The cell adhesion molecule BT-IgSF is essential for a functional blood–testis barrier and male fertility in mice

The Ig-like cell adhesion molecule (IgCAM) BT-IgSF (brain- and testis-specific Ig superfamily protein) plays a major role in male fertility in mice. However, the molecular mechanism by which BT-IgSF supports fertility is unclear. Here, we found that it is localized in Sertoli cells at the blood–test...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Pelz, Laura, Purfürst, Bettina, Rathjen, Fritz G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766970/
https://ncbi.nlm.nih.gov/pubmed/29123028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000113
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