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Cell-surface phosphatidylserine regulates osteoclast precursor fusion

Bone-resorbing multinucleated osteoclasts that play a central role in the maintenance and repair of our bones are formed from bone marrow myeloid progenitor cells by a complex differentiation process that culminates in fusion of mononuclear osteoclast precursors. In this study, we uncoupled the cell...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Verma, Santosh K., Leikina, Evgenia, Melikov, Kamran, Gebert, Claudia, Kram, Vardit, Young, Marian F., Uygur, Berna, Chernomordik, Leonid V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766907/
https://ncbi.nlm.nih.gov/pubmed/29101233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.809681
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