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Cell-surface phosphatidylserine regulates osteoclast precursor fusion

Bone-resorbing multinucleated osteoclasts that play a central role in the maintenance and repair of our bones are formed from bone marrow myeloid progenitor cells by a complex differentiation process that culminates in fusion of mononuclear osteoclast precursors. In this study, we uncoupled the cell...

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Vydáno v:J Biol Chem
Hlavní autoři: Verma, Santosh K., Leikina, Evgenia, Melikov, Kamran, Gebert, Claudia, Kram, Vardit, Young, Marian F., Uygur, Berna, Chernomordik, Leonid V.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766907/
https://ncbi.nlm.nih.gov/pubmed/29101233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.809681
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