Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML

Bone marrow vascular niches sustain hematopoietic stem cells (HSCs) and are drastically remodeled in leukemia to support pathological functions. Acute myeloid leukemia (AML) cells produce angiogenic factors, which likely contribute to this remodeling, but anti-angiogenic therapies do not improve AML...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Stem Cell
Main Authors: Duarte, Delfim, Hawkins, Edwin D., Akinduro, Olufolake, Ang, Heather, De Filippo, Katia, Kong, Isabella Y., Haltalli, Myriam, Ruivo, Nicola, Straszkowski, Lenny, Vervoort, Stephin J., McLean, Catriona, Weber, Tom S., Khorshed, Reema, Pirillo, Chiara, Wei, Andrew, Ramasamy, Saravana K., Kusumbe, Anjali P., Duffy, Ken, Adams, Ralf H., Purton, Louise E., Carlin, Leo M., Lo Celso, Cristina
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766835/
https://ncbi.nlm.nih.gov/pubmed/29276143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2017.11.006
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker