Rare ginsenoside Ia synthesized from F1 by cloning and overexpression of the UDP-glycosyltransferase gene from Bacillus subtilis: synthesis, characterization, and in vitro melanogenesis inhibition activity in BL6B16 cells

BACKGROUND: Ginsenoside F1 has been described to possess skin-whitening effects on humans. We aimed to synthesize a new ginsenoside derivative from F1 and investigate its cytotoxicity and melanogenesis inhibitory activity in B16BL6 cells using recombinant glycosyltransferase enzyme. Glycosylation ha...

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Veröffentlicht in:J Ginseng Res
Hauptverfasser: Wang, Dan-Dan, Jin, Yan, Wang, Chao, Kim, Yeon-Ju, Perez, Zuly Elizabeth Jimenez, Baek, Nam In, Mathiyalagan, Ramya, Markus, Josua, Yang, Deok-Chun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766694/
https://ncbi.nlm.nih.gov/pubmed/29348721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgr.2016.12.009
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