Targeting melanoma stem cells with the Vitamin E derivative δ-tocotrienol

The prognosis of metastatic melanoma is very poor, due to the development of drug resistance. Cancer stem cells (CSCs) may play a crucial role in this mechanism, contributing to disease relapse. We first characterized CSCs in melanoma cell lines. We observed that A375 (but not BLM) cells are able to...

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Publicado en:Sci Rep
Main Authors: Marzagalli, Monica, Moretti, Roberta Manuela, Messi, Elio, Marelli, Marina Montagnani, Fontana, Fabrizio, Anastasia, Alessia, Bani, Maria Rosa, Beretta, Giangiacomo, Limonta, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766483/
https://ncbi.nlm.nih.gov/pubmed/29330434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-19057-4
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