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Antinociceptive effects of mixtures of mu opioid receptor agonists and cannabinoid receptor agonists in rats: impact of drug and fixed-dose ratio

Pain is a significant clinical problem, and there is a need for effective pharmacotherapies with fewer adverse effects than currently available drugs (e.g., mu opioid receptor agonists). Cannabinoid receptor agonists enhance the antinociceptive effects of mu opioid receptor agonists, but it remains...

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Pubblicato in:Eur J Pharmacol
Autori principali: Maguire, David R., France, Charles P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766417/
https://ncbi.nlm.nih.gov/pubmed/29183835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2017.11.038
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