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Neurotrophin and FGF signaling adapter proteins, FRS2 and FRS3, regulate dentate granule cell maturation and excitatory synaptogenesis

Dentate granule cells (DGCs) play important roles in cognitive processes. Knowledge about how growth factors such as FGFs and neurotrophins contribute to the maturation and synaptogenesis of DGCs is limited. Here, using brain-specific and germline mouse mutants we show that a module of neurotrophin...

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Bibliografiske detaljer
Udgivet i:Neuroscience
Main Authors: Nandi, Sayan, Alviña, Karina, Lituma, Pablo J., Castillo, Pablo E., Hébert, Jean M.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766409/
https://ncbi.nlm.nih.gov/pubmed/29155277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2017.11.017
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