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Blocking the RecA activity and SOS-response in bacteria with a short α-helical peptide

The RecX protein, a very active natural RecA protein inhibitor, can completely disassemble RecA filaments at nanomolar concentrations that are two to three orders of magnitude lower than that of RecA protein. Based on the structure of RecX protein complex with the presynaptic RecA filament, we desig...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Yakimov, Alexander, Pobegalov, Georgii, Bakhlanova, Irina, Khodorkovskii, Mikhail, Petukhov, Michael, Baitin, Dmitry
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766188/
https://ncbi.nlm.nih.gov/pubmed/28934502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx687
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