Hypothermia increases aquaporin 4 (AQP4) plasma membrane abundance in human primary cortical astrocytes via a calcium/transient receptor potential vanilloid 4 (TRPV4)‐ and calmodulin‐mediated mechanism

Human aquaporin 4 (AQP4) is the primary water channel protein in brain astrocytes. Hypothermia is known to cause astrocyte swelling in culture, but the precise role of AQP4 in this process is unknown. Primary human cortical astrocytes were cultured under hypothermic (32 °C) or normothermic (37 °C) c...

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Dades bibliogràfiques
Publicat a:Eur J Neurosci
Autors principals: Salman, Mootaz M., Kitchen, Philip, Woodroofe, M. Nicola, Brown, James E., Bill, Roslyn M., Conner, Alex C., Conner, Matthew T.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Molecular and Synaptic Mechanisms
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765450/
https://ncbi.nlm.nih.gov/pubmed/28925524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.13723
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