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Effective Vortioxetine Dose Varies with Extent of Antidepressant Use Across Countries

OBJECTIVE: One of the possible explanations for the antidepressant resistance is tolerance to the effect of increasing synaptic serotonin. Vortioxetine is thought to work through a combination of two pharmacological modes of action: serotonin reuptake inhibition and modification of serotonin recepto...

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Detalles Bibliográficos
Publicado en:Psychopharmacol Bull
Main Authors: Tegin, Cuneyt, Tegin, Gulay, El-Mallakh, Rif S.
Formato: Artigo
Idioma:Inglês
Publicado: MedWorks Media Global 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765433/
https://ncbi.nlm.nih.gov/pubmed/29382958
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