Alda-1 Protects Against Acrolein-Induced Acute Lung Injury and Endothelial Barrier Dysfunction

Inhalation of acrolein, a highly reactive aldehyde, causes lung edema. The underlying mechanism is poorly understood and there is no effective treatment. In this study, we demonstrated that acrolein not only dose-dependently induced lung edema but also promoted LPS-induced acute lung injury. Importa...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Lu, Qing, Mundy, Miles, Chambers, Eboni, Lange, Thilo, Newton, Julie, Borgas, Diana, Yao, Hongwei, Choudhary, Gaurav, Basak, Rajshekhar, Oldham, Mahogany, Rounds, Sharon
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765414/
https://ncbi.nlm.nih.gov/pubmed/28763253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0342OC
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