The human PKP2/plakophilin‐2 gene is induced by Wnt/β‐catenin in normal and colon cancer‐associated fibroblasts

Colorectal cancer results from the malignant transformation of colonic epithelial cells. Stromal fibroblasts are the main component of the tumour microenvironment, and play an important role in the progression of this and other neoplasias. Wnt/β‐catenin signalling is essential for colon homeostasis,...

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Bibliografiske detaljer
Udgivet i:Int J Cancer
Main Authors: Niell, Núria, Larriba, María Jesús, Ferrer‐Mayorga, Gemma, Sánchez‐Pérez, Isabel, Cantero, Ramón, Real, Francisco X., del Peso, Luis, Muñoz, Alberto, González‐Sancho, José Manuel
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Molecular Cancer Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765413/
https://ncbi.nlm.nih.gov/pubmed/29044515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31104
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