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Harnessing the power of regulatory T‐cells to control autoimmune diabetes: overview and perspective

Type 1 diabetes (T1D) is a T‐cell‐mediated autoimmune disease resulting in islet β‐cell destruction, hypoinsulinaemia and severely altered glucose homeostasis. Although the mechanisms that initiate T1D still remain elusive, a breakdown of immune tolerance between effector T‐cells (T(eff)) and regula...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Yu, Hua, Paiva, Ricardo, Flavell, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765377/
https://ncbi.nlm.nih.gov/pubmed/29155454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12867
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