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Mechanisms of inactivation of the tumour suppressor gene RHOA in colorectal cancer
BACKGROUND: Reduced RHOA signalling has been shown to increase the growth/metastatic potential of colorectal tumours. However, the mechanisms of inactivation of RHOA signalling in colon cancer have not been characterised. METHODS: A panel of colorectal cancer cell lines and large cohorts of primary...
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| 出版年: | Br J Cancer |
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| 主要な著者: | , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5765235/ https://ncbi.nlm.nih.gov/pubmed/29206819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.420 |
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