Droplet digital PCR-based EGFR mutation detection with an internal quality control index to determine the quality of DNA

In clinical translational research and molecular in vitro diagnostics, a major challenge in the detection of genetic mutations is overcoming artefactual results caused by the low-quality of formalin-fixed paraffin-embedded tissue (FFPET)-derived DNA (FFPET-DNA). Here, we propose the use of an ‘inter...

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Publicado no:Sci Rep
Main Authors: Kim, Sung-Su, Choi, Hyun-Jeung, Kim, Jin Ju, Kim, M. Sun, Lee, In-Seon, Byun, Bohyun, Jia, Lina, Oh, Myung Ryurl, Moon, Youngho, Park, Sarah, Choi, Joon-Seok, Chae, Seoung Wan, Nam, Byung-Ho, Kim, Jin-Soo, Kim, Jihun, Min, Byung Soh, Lee, Jae Seok, Won, Jae-Kyung, Cho, Soo Youn, Choi, Yoon-La, Shin, Young Kee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765147/
https://ncbi.nlm.nih.gov/pubmed/29323170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18642-x
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