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IL-13 in LPS-Induced Inflammation Causes Bcl-2 Expression to Sustain Hyperplastic Mucous cells

Exposure to lipopolysaccharides (LPS) causes extensive neutrophilic inflammation in the airways followed by mucous cell hyperplasia (MCH) that is sustained by the anti-apoptotic protein, Bcl-2. To identify inflammatory factor(s) that are responsible for Bcl-2 expression, we established an organ cult...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Chand, Hitendra S., Harris, Jennifer F., Tesfaigzi, Yohannes
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765145/
https://ncbi.nlm.nih.gov/pubmed/29323189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18884-9
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