Skeletal Characterization of the Fgfr3 Mouse Model of Achondroplasia Using Micro-CT and MRI Volumetric Imaging

Achondroplasia, the most common form of dwarfism, affects more than a quarter million people worldwide and remains an unmet medical need. Achondroplasia is caused by mutations in the fibroblast growth factor receptor 3 (FGFR3) gene which results in over-activation of the receptor, interfering with n...

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Publicado no:Sci Rep
Main Authors: Shazeeb, Mohammed Salman, Cox, Megan K., Gupta, Anurag, Tang, Wen, Singh, Kuldeep, Pryce, Cynthia T., Fogle, Robert, Mu, Ying, Weber, William D., Bangari, Dinesh S., Ying, Xiaoyou, Sabbagh, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765052/
https://ncbi.nlm.nih.gov/pubmed/29323153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18801-0
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